update 29 days ago
Cell Biologist Technician for an Apprenticeship Contract F/M
  • Ref: ALTBIO/CELL/2021/03/WEB
Company presentation

Adocia is a clinical-stage biotechnology company that specializes in the development of innovative formulations of already-approved therapeutic proteins. Adocia's insulin formulation portfolio, featuring five clinical-stage products and three preclinical products, is among the largest and most differentiated in the industry.

Your mission

ADOCIA is recruiting for its R&D Department in Lyon:


Mission: Efficacy and biocompatibility evaluation of innovative formulations developed in ADOCIA.
The student will be working in the Biology department under the direct supervision of a research scientist and will take part in the mission assigned to the laboratory technicians of the department. Its main missions are :

-   ADOCIA formulation efficacy evaluation:

  • Potency measurements of ADOCIA formulations
  • Development of predictive in vitro models (vitro/vivo correlation)
  • Investigation of action mechanism of products developed in the company

-   ADOCIA formulations biocompatibility evaluation:

  • In vitro evaluation of formulations biocompatibility
  • Development of predictive in vitro models (vitro/vivo correlation)

-   Participation to the laboratory good practices (lab book, material and reagents orders, equipment and lab space maintenance)
The main techniques used will include:
-   Cell culture

  • Bio-assays
  • Cell line and primary cell cultivation and transfection
  • Proliferation assay, cytotoxicity assays
  • Marker expression assays (ELISA, ...) and reporter gene assays
  • Microscopy (phase contrast, epifluorescence)
  • Flow cytometry

-   Biochemical quantification:

  • Protein analysis method : ELISA, alphaLISA,...
  • Biochemical analysis (Western-blot, colorimetric quantifications)

-   Molecular biology:

  • Cloning
  • Gene expression analysis 
Expected profile

The skills required for performing these missions will be:

-  Technical skills

  • Following experimental protocols for validated in vitro assays 
  • Development of experimental protocols 

-   Oral and written skills for reporting results

-   Following safety and quality assurance rules

-   Ability to interact with colleagues, management and society personnel

For this « contrat d'alternance », it necessary to enjoy research, have a rigorous methodology and to like teamwork.

Adocia promotes excellence to become a partner of large pharmaceutical companies specialized in the innovative treatment of chronic diseases.

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