Scientist DMPK M/W


Adocia is a clinical-stage biotechnology company that specializes in the development of innovative formulations of already-approved therapeutic proteins. Adocia\'s insulin formulation portfolio, featuring four clinical-stage products and one preclinical product, is among the largest and most differentiated in the industry.

This position will work in close collaboration with management and multidisciplinary teams under the supervision of the Biology/PKPD Director. The role will be to:
- Provide scientific and technical expertise to streamline the DMPK strategy for Adocia\'s BioChaperone technology,
- Identify potential risks and provide mitigation strategies. Being proactive, working with teams to resolve project issues and ensure timely and efficient progression of projects,
- Collaborate closely with nonclinical team, CMC, chemistry, toxicology, and other functions to move projects in an efficient manner,
- Coordinate studies with external service providers for preclinical in vitro and in vivo studies,
- Analyse, interpret and report data from non-clinical DMPK, ADME, TK and PK studies, and contribute to IVIV correlations,
- Prepare and/or review TK, ADME and DMPK components of internal documents, briefing books, regulatory submission documents (e.g. IMPD, IB, IND…) and response to regulatory queries,
- Work collaboratively with the Adocia\'s PK/PD scientists supporting ongoing projects.

You should possess the following:
- Master or PhD in Drug Metabolism and Pharmacokinetics, or a related discipline,
- At least 5 years of relevant experience in the Pharmaceutical/Biotech industry or Contract Research Organizations,
- A strong understanding of in vitro and in vivo DMPK assays, methods and models,
- Polymer DMPK experience - this is a must,
- Some experience and expertise in modeling such as PK/PD and PBPK is desirable plus,
- Strong organizational skills and enjoys working in cross functional teams,
- Proficiency in English, written and spoken,
- Proficiency in French (spoken) is a plus,
- Strong inter-personal and effective team work skills.
Driven by Science and Innovation, you are inquisitive and enjoy problem solving. You are creative, optimistic and enjoy working in a team environment. You\'re enjoy working in a highly-paced and ambitious industrial environment
Adocia promotes excellence in order to bring the best drugs to the patients and to become a valuable partner to large pharmaceutical corporations.